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Neem extracts are among the most powerful anti-fungal plant extracts, and Neem has been considered an effective treatment for fungal infections in Ayurvedic medicine. Compounds found in the Neem leaf help control several fungi which attack humans, most notably, those that cause athlete's foot, ringworm, and thrush. Wash or bathe with a Neem soap, apply Neem oil, Neem lotion, Neem cream or Neem salve directly to the affected areas.