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While there is no cure for psoriasis, Neem oil may be effective treating the condition. Neem moisturizes and protects the skin while helping to heal lesions, scaling, and irritations. Add several tablespoons of Neem oil or Neem leaf powder to a warm bath and soak for 20 minutes, Bath or shower with Neem soap, apply a Neem lotion, cream, or salve several times a day to affected areas. Consider a Neem leaf extract or capsule to help boost the immune system.